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A study conducted in Ontario reveals that grapefruit, orange and apple juices can make the drugs less effective during medication.


Some Fruit Juices Lower Drug Effect
Last Updated: 21-08-2008 15:09:49 IST
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According to a report presented in 236th annual meeting of the American Chemical Society on Philadelphia, Pennsylvania, grapefruit, orange and apple juices can make the drugs less effective during medication. Also, the study shows that these juices can harm the body's ability to absorb certain medications. Researchers opine that these fruit juice wipe out the beneficial effects of medicine.
 
Prof. Bailey, Clinical Pharmacology (University of Western Ontario) expressed his concern that the loss of benefit of medications essential for the treatment of serious medical conditions is major issue. In the study healthy volunteers took fexofenadine, an antihistamine used to fight allergies, along with either a glass of grapefruit juice, a glass of water with naringin, or plain water. And, conclusively, the grapefruit drinkers absorbed only half the amount of fexofenadine, compared simple water takers.
 
David Bailey, the leading researcher on the feat commented that they discovered that grapefruit and these other fruit juices substantially decrease the oral absorption of certain drugs undergoing intestinal uptake transport. Also, these juices have decreasing effectiveness impact towards heart disease, cancer, organ-transplant rejection and infection drugs.
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