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The body has numerous physical and biochemical ‘fence’, which helps the cell to retain their normal positions. But in cases of people, where breast cancer metastasizes, these protective ‘fences’ crash, leading to the spread of cancer to bones, liver or brain.
The drugs which are available now can help only in stalking the uncontrolled division of cancer cells within mammary ducts, but they do not help in restraining the spread of cancer outside the breasts.
A researcher from Northwestern University Feinberg School of Medicine (NUFSM) has found a way to strengthen the breast's "fence" to prevent cancer from metastasizing.
Researcher Seth Corey of the NUFSM and principal study investigator mentions that a combination of a drug used for the treatment of leukaemia and breast cancer drug can act as a ‘new chemotherapy cocktail’ which can restrain the metastasis of cancer outside breast cells.
"This is an entirely new way of targeting a cancer cell," said Corey, professor of cancer biology and chemotherapy at the Feinberg School.
While conducting the research, he discovered that dasatinib, sued for the treatment of leukaemia when combined with doxorubicin, the breast cancer drug, has the potential for restricting the invasion of breast cancer cells to 50%.
These findings were recently reported in the British Journal of Cancer.
